I know, it won't let me hit F1, if I do, it does nothing, no, trainer cannot find game, no trainer activated, nothing. It seems like the devs disabled the F1 key period if the game is launched.
Hmm. Shouldn't affect the F1 key at all, whether it's bound in-game or not. Try the trainer customizer to re-assign hotkeys if you are sure it's this.
i think the Trainer Customizer tool given to us by CH is a very helpful tool. Shindou should try it out.