Actually I'm a dumb dumb. I just noticed all the settings after the update were wayyyyy off from what was set before. I used GeForce Experience to quickly optimize those settings and the game works fine with the trainer.
UPDATE: The verify completed and still crashed....so I looked to the FarCry subreddit and found many other users reporting the same crashing issue as I did.
I ended up updating my NVIDIA driver to the one that came out yesterday (Version 496.49) and then ALSO disabling the in-game Ubisoft overlay.
The crashing is gone and I didn't have to start up a new game...I resumed my existing game just fine. Good luck to everyone!
[Edited by b0r3dguy, 10/27/2021 6:43:14 PM]
Please delete the trainer, custom keys, debug folder where the trainer resides and all files in
Learn how to make your own Trainer Cleaner for the above paths here.
Reboot PC to clear excess memory, get a fresh copy of latest trainer and extract it. Run trainer as admin, read the instructions and try again. At times, a new game may be needed to resolve failed options if the data in your save file was altered. Use on a new game and test the option. If it now works, quit to main menu and load your save and try it again. May also need to run the game without the trainer first and play a bit so the save file gets updated to use possible new values. This typically will resolve the issue.
This cleaner is also part of the new Cheat Happens Trainer Manager 2.0, it is found in the settings and has an easy to use one button click feature.