Have both 3.1 and latest .NET CORE and FRAMEWORK
.NET Core 3.1 Desktop Runtime x86
Link.NET Core 3.1 Desktop Runtime x64
Link.NET Core Current Runtime x86
Link.NET Core Current Runtime x64
Link.NET Framework (get latest)
Link(
Both of the Net-Core MUST be installed x86 and x64)
Reboot PC When done.
If they still don't start after tall these are installed, Dakkatakk is right, usually your security software.
Extract trainer and make sure trainer/launcher/editor is in a folder excluded from virus scans. Empty quarantine folder if needed or set anything trainer related (paths and EXE's) to ALLOW. Disable any Live/Active/Real-Time tools which may trigger false positives in security software which may terminate the game/trainer when it's activated or options used.
C:\Users\USERNAMEHERE\Cheathappens
may need to be added to exclusions as well. Run trainer as admin, read the instructions and try again.
Anti-virus help page.
LinkNote: Exclusions may need to be added to both Widows Defender and any 3rd party software you use.