I did try the 1.5.0 CH Trainer on the 1.5.1 updated game today (Oct 18) and the options I tested work fine in the main game and in the Atlantis DLC too. I didn't test all the options but Numpad 1, 2 and 3 work ok. Those are god mode, super stealth and super damage. The stealth option works but I turned it off almost all the time to make it easier for quests to complete as the readme recommends. Sorry I didn't try the other options but it's a start, and I hope the others work for you.
I'm using the Uplay only game version not the Steam/Uplay one. I uninstalled the game from Steam a few weeks ago so I don't know if the latest trainer works on the updated Steam/Uplay game.
There is a Steam & UPlay version and a UPlay PLUS version so you mean you tried the UPlay Plus version?
The update was only 400 MBs and it was mostly Bug Fixes so most likely the trainers still work as designed.
[Edited by Jaks, 10/18/2019 8:52:41 PM]