Very same problem here. I can get the trainer to activate and in fact all the F1-F12 options work but NONE of the number pad options are functioning/registering as being activated in game. I have ensured the issue is not with my keyboard. The number pad is working fine. But I have not had this issue before the latest version of the trainer. Windows 10 as well, running the trainer as administrator, no firewalls or antivirus.
I did that was well but still no luck. The old version, which I still have in zipped file, works fine. The new one, though, is unresponsive for the numpad.
EDIT: Actually, nevermind. For whatever reason, after restarting my computer, it is working properly now. Must have been something with Windows 10 not wanting to let it run or somesuch. Can confirm it's working now, though.
[Edited by MTCason, 8/17/2016 8:43:16 AM]
Trainer works fine with current version of game. At least we haven't receive any complaints otherwise from the 10,000+ premium subscribers that are using the trainer.