I had a longer post, but the anti-hacking bit on submitting lost it for me.
Short version, game (but not trainer) crashes when the "Freeze Timer" mode is on and then the game world is refreshed.
1: Load savegame, pause game, F1, activated trainer, press "[", un-pause game, and game crashes.
2: Load savegame, don't pause, F1, activated trainer, press "[", fast-travel, and game crashes.
Verified the trainer and it works as expected.
You need to follow the instructions as follow:
Launch the trainer first, then launch the Game and then Press F1 at the Main Menu.
Listen for "Activated".
You need to run the trainer as an administrator.
If you do as stated in the read-me file it will function fine.