No you cannot nor in any other Fable game. This may be able to happen in the next Fable game but then again I am not sure it will
if they make a fable 2 then i agree with thealchemist
they will make a fable two and u can use guns (like muskets or those crappy old pistles)
lol u think old handguns r crappy i will take 1911 colt over any handgun today the 1911 colt is one of the best handguns in the wrold