I get CTD's when:
Loading the main menu
Loading a level
Loading a save game
Saving a save game
Entering a new area
Fighting an enemy and
If I so much cough when playing.
The crashes are not trainer related (but are more frequent when any trainer or any GPU/CPU overclock is enabled) but because of the fact of the PC port being a complete coding trainwreck as Bethesda/Arkane are purely console centric and I bet even outsource the PC porting to incompetant imbeciles.
@ Hoover
You and I chatted about this quite a bit. For me, it was only loading an older save game. I'm also wondering about our OS differences. I'm on Win 7, what are you using now?