I just dloaded and extracted Wasteland 2 and it's fine. You need to disable your AV (esp real time scanning) or add to your exclusion list.
This way all your trainers should automatically be excluded (as opposed to having to whitelist each trainer individually).
OT: If you are looking for a free antivirus, I'm currently using Avira and I've yet to have any AV related trouble with my CH trainers.
* Updated game trainers and cheats daily
* Get notified when new cheats are added
* Request which games get new trainers
* Priority support with any problem