I only used the upgrade points at the start to upgrade HP to max level. After that I finished the game without the trainer( zero crashes/glitches). Now that I have finished the game I am going to use the trainer to finish off the side quests etc so I will see if I get any CTD issues with it on.
If you have the version with Securom and what not on it, chances are, you'll CTD and eventually corrupt your save.
On another note, big thanks to Cal and PWiz for the awesome job, but is there possibly going to be any trainer for those of us unfortunate to have the screwed up retail version? --I'm checking before i go purchase a Steam version.
Not sure what the cause is, just going by previous posts. I'll wait for either a working trainer to be released on here, or a 'fixed' exe, trying to avoid getting it on Steam. I beat the game on Xbox with no cheats/trainers, really looking to have 'fun' with it on PC.