just to add a little detail to what users like myself are seeing:
the first three times I try to open the trainer it takes minutes and then the trainer process exits silently. the third time the trainer takes minutes to open, way longer than any other trainer, and then finally comes up.
at the in-game menu if I hit f1 it says please wait...then the game crashes. I try again, open up the game, click activate trainer in the trainer itself, the game crashes. I look through the options in the trainer, that useless Ingame Overlay has become checked again even though I shut it off already, I uncheck it. then I hit the activate trainer button and it says "trainer activated".
You're right, all the trainers I've downloaded in the last couple months are also taking forever to open now. Setting defender exclusions for them isn't helping, either.
No mods whatsoever.