I use Malwarebytes as well and it isn't causing any issues for me.
Game runs good for me and i have an ultra-wide monitor though my resolution is set to 3840-1080 and i have no issue, the game picked the best resolution settings to play game though HDR is not enabled even though my monitor is set for HDR.
I have AMD Ryzen 7 3700x
RTX 2080 TI
32 GB RAM
Going to test with trainer now that its available.
Hopefully you get your issue resolved.