Works where I tested it. I guess maybe there are more types of doors that it doesn't work for. Keep in mind that opening doors ahead of time could also break scripts..
"Numpad 7: Easy Open Rune Doors - to use this make sure you toggle on
BEFORE you load into the game, preferably at the main menu.
This removes one of the most annoying parts of the game,
namely having to run around and search for matching scenery
in the game to these runes on the doors. If this is on,
then simply walk up to the door, focus on it to reveal
the runes, then USE the door to enter it. No more wasting
100 hours running around solving annoying puzzles. This
mainly works on the doors with two pictures, such as the
doors in the FIRE area, mainly RUNE doors. May not work on
all doors, such as those that require illusion alignment."
I am also experiencing this. Latest Steam version here. Easy Open Rune Door doesn't work.