I have done most the troubleshotting even got rid of my Avast n now have MS essentials & Malwarebytes anti-malware & winders defender is disabled (Windows 7 Ult 64bit)
& its all the trainers even the 1s that worked a year ago. Wot the heck is going on
Please disable/uninstall all antivirus, firewall and other security software including browser addons and extensions. Right click "Run as Administrator" on trainer and game. Please note that some security products may still block access to trainer injection even when disabled and must be completely uninstalled. If this is the case, please contact the product vendor for instruction on the proper way to prevent the trainers from being blocked by their software or find a better alternative.
I have exactly the same setup as you, MSE, MWB and Win 7 and all the CH trainers work perfectly for me.
The one thing that might be a little different is the MWB-Anti-Malware product. I'm not sure which version you're using but I'm using the free version. That might give you something to check at least. Otherwise, as PWiz stated, something is blocking trainers on your end. Win 7, MSE and this MWB are all extremely accepting of CH trainers and I've gotten along that way for years without any problems.
* Up to 400 new and updated trainers monthly
* Manage and update trainers through one app
* Request which games get new trainers
* Priority support with any problem