STEAM Version 2.10.25624 Yes, I have followed the troubleshooting guide. I will upload a save game with the lighting effect for substrate, but I can't enable any of the other options and can't provide a save with any of those activated. Sorry.
I have reported issues since v2.2 with unit and building health values blinking then returning to normal, however I found the substrate to turn into a shining sun like object if you set the value of the unit's health too high, this also happens if you upgrade there health through quanta upgrades. To avoid customize super unit health to a lower value.