originally posted by Nalgus_Peludo
I did some messing around and I think the issues lies with the unlimited HP making the hearts go back to what they previously were.
What I did was use Sampson(3HP), got a 1 heart deal with the devil now making it so I had 2 hearts. I turned OFF the unlimited HP, used super HP and now had 6 red HP. I turned the unlimited HP back on and reverted to 2 red hearts.
I only did this with Sampson but I will try other characters.
I do not have everything unlocked but will gladly give you my save file if I receive a send location.
im having these issues aswell, heres my save folder and exe www.mediafire.com/download/sxi5xqy1840jlx8/isaac.7z