Did you right-click on the trainer and run As Admin?
Yes, I've run as administrator and also exclude the trainer folder from any windows defender and firewalls lists. If this helps I have not made it out of the prologue yet. Does this matter?
Update: I've made it out of the prologue and it still insists the game is not running. No sounds at all when F-1 is pressed.
[Edited by rusty5551, 10/25/2015 2:40:30 PM]
Tried running everything as administrator and no help.
[Edited by rusty5551, 10/25/2015 3:08:01 PM]