Hey ishist, the following steps worked for me.
( 1 ) Set the save file to Read-Only.
( Right Click >> Properties >> Read-Only tickbox )
( 2 ) Start game, and load the save game profile.
( 3 ) Once loaded, (your in-game character is controllable) minimize the game, and unmark the save file Read-Only box.
( 4 ) Resume playing, and continue to play until the game autosaves.
( 5 ) Once an autosave has completed, you should be free to close the game.
Please reply to this post if you're successful, or unsuccessful.