I seem to be having the same issue. Otherwise it works.
Option 6 does seem to be wonky.
For me, it simply disables mouse input. I can run around forward, backward, etc but am always facing in the same direction.
The game also becomes a bit unstable when this happens. I hit ESC to reload a checkpoint (which fixed it the first time) and the game crashed instead of going to the menu. That happened twice.
Other options seem to work, though.