If you use the dll fix, DO NOT USE DUALVIEW aka 2 screens, it doesnt support it. Meaning you have to disable the one you are not playing on.
Im on the point of giving up this game for the time being, mostly through a game but the quest bugs annoy the crap outta me. I still have to use hours to plan my play what order to do quests and how before i spend an hour doing them so they won't break or some quests won't be unavailable. (Yes im a bit perfectionist i know)
Dual screens wont work yep and personly I think its a pain. But any hows. I am amazed people are having so many problems I have not come accross any except one the ghost ghoul lol. Plus I stick to a certin path, E.g. NCR first complete the game on NCR's side. then start again as another dude.