well, it depends on the amount of tooth paste.
[Edited by springer13, 9/12/2010 5:48:35 AM]
Yeah pretty much that.
If it's a brand new tube filled with toothpaste, I press a little at the top. When half of it is gone, I squeeze at the middle. When there's only a quarter of it left, I squeeze at the bottom all the way to the top.