I can't get the trainer to work either, I believe I followed everything right :
I run the trainer first I launch the game I press F1 when on the main menu I hear "activated" I load a mission I crash to desktop with a blizzard report error window as soon as I enter the game
Am getting the same problem. Loading Ultimate Trainer 1.0.1.16195 and am playing updated SC2. Exact same problem happens to me. I hear activated. I go to start campaign, and game crashes.
No third party AV running, nor security apps. Win7 x64, have also tried setting the trainer to compatibility mode, it's also crashing same as the other two guys on this page are describing.
I deleted the trainer, reloaded the trainer, and now it is working. Not sure what happened, but I did not change AV settings. All I did was reload the trainer, and restarted the computer.