the trainer does work, i am using original mega trainer on the steam non patched product. One thing I have noticed is that when you enable Super Freeze/Burn/Shock (+) enemies can't see you and little sisters won't gather adam, best thing to do is leave it off, use keybind cheat to get all plasmids and tonics
I believe this is/was a bug in the trainer or documentation, use - for the super freeze/burn/shock, + makes you invisible to enemies.