Hi, a few years ago when I was using McAfee I encountered some problems with certain trainers. After reading through some forums I went with Windows Firewall/Anitvirus (Windows 10)and Malwarebytes. Although Malwarebytes occassionally causes problems with older trainers, my computer and trainers run close to perfectly. I found McAfee itself was the problem as well as cumbersome and it slowed down my PC.
This is exactly what i do and have no issues.