How? All my other trainers work perfectly and this does not open.
Then something is blocking it, like Windows Defender or some other AV software.
Here is a screenshot of the latest Subnautica trainer running just fine on my Windows 10 PC with anniversary update.
Link
Need for Speed: Shift fails to run.
That trainer was never updated to windows 8/10 compatibility. Contact Caliber about that.
Stalker - Call of Pripyat please (no "activated" noise when pressing F1).
unrelated
Kingdom of Anapur: reckoning. Trainer crashes after opening. Origin version
That trainer is not compatible with Windows 8/10, only the Steam version. You can try contacting Caliber for a fix.