Definitely don't play it unless you've played the other two and have save files to transfer over. The default choices the game makes for your backstory are very detrimental to the game itself, and having made your own choices in the previous games makes for a more personal experience.
Unless, you know, you're just in it for the explosions and action sequences. In that case, by all means play the **** out of it.
I don't know why but while I recognize that she is talented, I absolutely loathe that kind of singing voice. I can't quite wrap my head around why, but I cringe and mute everything when I hear anything remotely similar to that specific kind of singing.