Mine is an EVGA. I haven't seen any issues thus far. I did not do a fresh install nor a refresh nor anything. I put it in and got the drivers (I don't see any reason not to do this since Windows has been plug-and-play since Windows 98).
For the 4k resolution: If you have Windows 7, don't get one. Windows 7 has some shoddy DPI support for high resolutions like that. If you have Windows 8 and can live with not gaming at 4k (you can 4k everything else) then go ahead if you have the money and really want it. One of the new features that isn't advertised much with Windows 8 is the massive improvement for high DPI support (you will need to restart your computer if you hot swap your monitors out).
I think I have the Samsung model that you're talking about but I got mine via direct import so the menu's are not in English (they are in Korean) which is no issue to me. I don't know if English models exist. One thing I will caution you is that they require color calibration to display colors accurately if you do any work that involves the need for color accuracy (otherwise it's not that big of a deal).
Be careful with the temps on that thing. I have one as well and it will cook itself or other components before it'll start showing performance limitations and more often then not you'll only find out when your computer turns itself off in desperation.
My experience in high temps was attempting to play games at 4k resolution though so doubtful you'll see the same thing. It did play them at 4k no problem. Had to turn it down to 1440p so it wouldn't constantly be on fire.
Always have the car in your driveway when possible. Legally the street belongs to the city and is fair game for getting a DOT tag or a ticket if someone complains. Your driveway is private property and is untouchable.